Cinnamon will help to support healthy blood sugar,
triglyceride and cholesterol levels with all metabolic syndrome and diabetic
patients.
1) Khan A MS,PHD, Cinnamon improves glucose and lipids of people with Type 2
diabetes. Diabetes Care, Vol 26:12, Dec 2003
Curcumin may fight Alzheimer's Disease
The pigment that gives curry spice its yellow hue may also
be able to break up the "plaques" that mark the brains of Alzheimer's disease
patients, early research suggests.
Scientists found that curcumin, a component of the yellow
curry spice turmeric, was able to reduce deposits of beta-amyloid proteins in
the brains of elderly lab mice when taken orally.
In addition, when the researchers added low doses of
curcumin to human beta-amyloid proteins in a test tube, the compound kept the
proteins from aggregating and blocked the formation of the amyloid fibers that
make up Alzheimer's plaques.
Accumulation of beta-amyloid proteins in the brain is one
of the hallmarks of Alzheimer's disease.
The new findings suggest that curcumin could be capable of
both treating Alzheimer's and lowering a person's risk of developing the
disease, said study co-author Dr. Gregory M. Cole of the University of
California Los Angeles and the Greater Los Angeles Veterans Affairs Healthcare
System.
Cole and his colleagues have received funding to begin a
small trial in humans suffering from Alzheimer's disease.
"The big question is how high are the doses we need to
fight Alzheimer's and are they really safe in elderly patients?" he said.
The current findings, published online recently by the
Journal of Biological Chemistry, add to the body of research pointing to
curcumin's medicinal value. Long used as part of traditional Indian medicine,
curcumin is now under study as a potential cancer therapy, and animal research
has suggested the compound might serve as a treatment for multiple sclerosis and
cystic fibrosis.
Interest in curcumin as an Alzheimer's therapy grew after
studies found low rates of the disease among elderly adults in India, where
curry spice is a dietary staple.
Curcumin is structurally similar to a stain known as Congo
red, which is used by pathologists to identify amyloid protein in autopsied
brain tissue in order to confirm a diagnosis of Alzheimer's disease after a
patient's death.
Curcumin can also stain amyloid deposits, Cole said, but
it has the additional ability, when eaten or injected, to cross into a living
animal's brain and bind to amyloid deposits.
What's more, he explained, curcumin is an antioxidant and
anti-inflammatory agent, and it appears to counter the oxidative damage and
inflammation that arises in response to amyloid accumulation.
"It attacks both the amyloid and the response to amyloid,"
Cole said.
Because oxidative damage and inflammation mark a number of
diseases of aging - such as arthritis and the buildup of plaques in the heart's
arteries - Cole said he and his colleagues hope that curcumin eventually proves
useful for a range of age-related conditions.
SOURCE: Journal of Biological Chemistry, online Dec. 7,
2004.